Metalloenzymology research in the Banerjee lab

At Auburn

Before Auburn

  1. Cutsail, G. E., 3rd; Banerjee, R.; Rice, D. B; Stepanic, O. M; Lipscomb, J. D.; DeBeer, S. Determination of the iron(IV) local spin-states of the Q intermediate of soluble methane monooxygenase by Kb X-ray emission spectroscopy. J. Biol. Inorg. Chem. 2022, 27, 573-582
  2. Jones, J. C#.; Banerjee, R#; Semonis, M. M.; Shi, K; Aihara, H.; Lipscomb, J. D. X-ray crystal structures of methane monooxygenase hydroxylase complexes with variants of its regulatory component: Correlations with altered reaction cycle dynamics. Biochemistry 2022, 61, 21-33 (# co-first authors)
  3. Banerjee, R; Srinivas, V; Lebrette, H. Ferritin-like proteins: A conserved core for a multitude of enzyme complexes. In Subcell Biochem, ed.; Harris, J. R.; Marles-Wright, J., Eds. Springer, Cham: 2022; Vol. 99, pp 109-153.
  4. Jacobs, A.; Banerjee, R.; Deweese, D.; Braun, A.; Babicz, J.; Gee, L.; Sutherlin, K.; Böttger, L.; Yoda, Y.; Saito, M.; Kitao, S.; Kobayashi, Y.; Seto, M.; Tamasaku, K.; Lipscomb, J. D.; Park, K.; Solomon, E. I. Nuclear Resonance Vibrational Spectroscopic (NRVS) Definition of the Fe(IV)2 Intermediate Q in Methane Monooxygenase and its Reactivity. J Am Chem Soc 2021, 143, 16007-16029
  5. Jones, J. C.; Banerjee, R.; Shi, K.; Semonis, M. M.; Aihara, H.; Pomerantz, W. C. K.; Lipscomb, J. D. Soluble Methane Monooxygenase Component Interactions Monitored by 19F NMR. Biochemistry 2021, 60, 1995-2010.
  6. Banerjee, R.; Lipscomb, J. D. Small-Molecule Tunnels in Metalloenzymes Viewed as Extensions of the Active Site. Acc Chem Res 2021, 54, 2185-2195.
  7. Jones, J. C.; Banerjee, R.; Shi, K.; Aihara, H.; Lipscomb, J. D. Structural studies of the methylosinus trichosporium OB3b soluble methane monooxygenase hydroxylase and regulatory component complex reveal a transient substrate tunnel. Biochemistry 2020, 59, 2946-2961.
  8. Srinivas, V#.; Banerjee, R#.; Lebrette, H.; Jones, J. C.; Aurelius, O.; Kim, I. S.; Pham, C. C.; Gul, S.; Sutherlin, K. D.; Bhowmick, A.; John, J.; Bozkurt, E.; Fransson, T.; Aller, P.; Butryn, A.; Bogacz, I.; Simon, P.; Keable, S.; Britz, A.; Tono, K.; Kim, K. S.; Park, S. Y.; Lee, S. J.; Park, J.; Alonso-Mori, R.; Fuller, F. D.; Batyuk, A.; Brewster, A. S.; Bergmann, U.; Sauter, N. K.; Orville, A. M.; Yachandra, V. K.; Yano, J.; Lipscomb, J. D.; Kern, J.; Hogbom, M. High-resolution XFEL structure of the soluble methane monooxygenase hydroxylase complex with its regulatory component at ambient temperature in two oxidation states. J Am Chem Soc 2020, 142, 14249-14266. (# co-first authors)
  9. Banerjee, R.; Jones, J. C.; Lipscomb, J. D. Soluble methane monooxygenase. Annu Rev Biochem 2019, 88, 409-431.
  10. Cutsail, G. E., 3rd; Banerjee, R.; Zhou, A.; Que, L., Jr.; Lipscomb, J. D.; DeBeer, S. High-resolution extended X-ray absorption fine structure analysis provides evidence for a longer Fe…Fe distance in the Q intermediate of methane monooxygenase. J Am Chem Soc 2018, 140, 16807-16820.
  11. Castillo, R. G.; Banerjee, R.; Allpress, C. J.; Rohde, G. T.; Bill, E.; Que, L., Jr.; Lipscomb, J. D.; DeBeer, S. High-energy-resolution fluorescence-detected X-ray absorption of the Q intermediate of soluble methane monooxygenase. J Am Chem Soc 2017, 139, 18024-18033.
  12. Hatzinger, P. B.; Banerjee, R.; Rezes, R.; Streger, S. H.; McClay, K.; Schaefer, C. E. Potential for cometabolic biodegradation of 1,4-dioxane in aquifers with methane or ethane as primary substrates. Biodegradation 2017, 28, 453-468.
  13. Oloo, W. N.; Banerjee, R.; Lipscomb, J. D.; Que, L., Jr. Equilibrating (L)Fe(III)-OOAc and (L)Fe(V)(O) Species in Hydrocarbon Oxidations by Bio-Inspired Nonheme Iron Catalysts Using H2O2 and AcOH. J Am Chem Soc 2017, 139, 17313-17326.
  14. Banerjee, R.; Komor, A. J.; Lipscomb, J. D. Use of isotopes and isotope effects for investigations of diiron oxygenase mechanisms. Method Enzymol 2017, 596, 239-290.
  15. Banerjee, R.; Proshlyakov, Y.; Lipscomb, J. D.; Proshlyakov, D. A. Structure of the key species in the enzymatic oxidation of methane to methanol. Nature 2015, 518, 431-434.
  16. Banerjee, R.; Meier, K. K.; Munck, E.; Lipscomb, J. D. Intermediate P* from soluble methane monooxygenase contains a diferrous cluster. Biochemistry 2013, 52, 4331-4342.

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